Thank you for your interest in the Mechanisms of Early and Late Postpartum Hypertension in Human Preeclampsia study. We call it "MONITOR" for short.

We know that some women who have been told they have preeclampsia or HELLP during a pregnancy go on to develop chronic hypertension. We don't know which women who have been diagnosed with preeclampsia will go on to develop chronic hypertension or why it happens.

The purpose of the MONITOR study is to try to begin to answer these questions. Therefore, we are inviting women who have been diagnosed with preeclampsia, eclampsia, or HELLP syndrome to consider beeing part of this research study.

We are also inviting women who have NOT been diagnosed with preeclampsia, eclampsia, or HELLP syndrome to participate in the study. The group will be used as the comparitor group.

Participating in the study involves coming to our lab at the University of Iowa Hospitals and Clinics in Iowa City, IA for one 3-hour visit.

At this visit, we will do non-invasive testing of your blood vessels, cognitive testing (task-based testing), and ask you to complete questionnaires regarding your health history and your activity level.

We will also send you home with two types of blood pressure cuffs, one you wear for 24 hours and the other you will use to take your blood pressure twice-a-day for seven days. We will also send you home with a small, waterproof physical activity monitor that will be adhered to the thigh with for 7-days. You would be provided postage-paid mailers to return the blood pressure cuffs and activiy monitor so you do not need to come back to our lab.

There is no cost for participating in this study, in other words you will not be charged for any of these tests and the results will not go into your medical records. We will compensate $100 for your time and effort involved in the study. We will compensate you $50 for completing the study visit in our lab and $50 when we receive both blood pressure cuffs from you.

You must be between the ages of 18 to 45 years to participate and must have delivered a child within the past four years. You cannot be currently pregnant. You must be in stable health.

Complete the information below if you are interested in participating in this study.

Thank you for your time and consideration.

Sincerely,

Mark Santillan MD, PhD, FACOG, FAHA, Associate Professor Department of Obstetrics & GynecologyUniversity of Iowa Health Care

Iowa City, IA 52242

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